| Alias |
BZIP28 |
| TF Classification |
| FioreDB | bZIP (Click to show phylogenetic tree) |
| RARTF | bZIP / ABSCISIC ACID-INSENSITIVE5 |
| AtTFDB | bZIP |
| PlnTFDB | bZIP (v3.0), bZIP (v1.0) |
| DATF | bZIP |
|
| TAIR short description |
Basic-leucine zipper (bZIP) transcription factor family protein (.1) |
| TAIR annotation |
Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment. (.1) |
| Gene model |
|
| Entry clone (w/o stop) |
IE_05E09_x |
| External link |
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| Gene Ontology (GO) |
| (C) 16020: other membranes |
->membrane |
| (P) 30968: other cellular processes |
->endoplasmic reticulum unfolded protein response |
| (P) 34976: other cellular processes |
->response to endoplasmic reticulum stress |
| (F) 3677: DNA or RNA binding |
->DNA binding |
| (F) 3700: transcription factor activity |
->transcription factor activity, sequence-specific DNA binding |
| (C) 48471: other cytoplasmic components |
->perinuclear region of cytoplasm |
| (C) 5634: nucleus |
->nucleus |
| (C) 5635: nucleus |
->nuclear envelope |
| (C) 5654: nucleus |
->nucleoplasm |
| (C) 5737: other cytoplasmic components |
->cytoplasm |
| (C) 5783: ER |
->endoplasmic reticulum |
| (P) 6355: transcription,DNA-dependent |
->regulation of transcription, DNA-templated |
| (P) 6986: response to stress |
->response to unfolded protein |
| (P) 6990: other cellular processes |
->positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response |
| (P) 9408: response to stress |
->response to heat |
|
| miRNA/tasiRNA |
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| Orthologs |
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Type |
| Ia |
Ib |
II |
III |
Total |
| poplar |
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| soybean |
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| rice |
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| sorghum |
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| physcomitrella |
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| Total |
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0E0 |
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| Repression motif |
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Repression motif
in putative orthologs |
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| Status |
| Plasmid construction | -> done |
| Plasmid construction | -> done |
| Transformed | -> done |
| T1 seed harvested | -> done |
| T2 seed harvested | -> done |
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| CRES-T phenotype from individual project
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| CRES-T phenotype from publication |
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| CRES-T phenotype from bulk project |
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Phenotype in ornamental plants
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| Comment |
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