WUSCHEL 1, WUSCHEL, Homeodomain-like superfamily protein (.1)
TAIR annotation
Homeobox gene controlling the stem cell pool. Expressed in the stem cell organizing center of meristems. Required to keep the stem cells in an undifferentiated state. Regulation of WUS transcription is a central checkpoint in stem cell control. The size of the WUS expression domain controls the size of the stem cell population through WUS indirectly activating the expression of CLAVATA3 (CLV3) in the stem cells and CLV3 repressing WUS transcription through the CLV1 receptor kinase signaling pathway. Repression of WUS transcription through AGAMOUS (AG) activity controls stem cell activity in the determinate floral meristem. Binds to TAAT element core motif. WUS is also involved in cell differentiation during anther development. (.1)
LEHRRTLPLFPMHGED at 253/292 in AT2G17950.1 VRPCASLELRLN at 285/292 in AT2G17950.1
Repression motif in putative orthologs
TREPETLPLFPVVFVG at 199/289 in rice Os019381 (Type Ib)
PAAGTSLELTLSSYYC at 269/289 in rice Os019381 (Type Ib)
AEKIETLPLFPMHGED at 205/264 in poplar Pt002935 (Type Ib)
TTSRTSLELSLYSYNG at 249/264 in poplar Pt002935 (Type Ib)
TRAPETLPLFPTGGDD at 221/327 in sorghum Sb014806 (Type Ib)
DASAASLELSLSSWCS at 310/327 in sorghum Sb014806 (Type Ib)